Michael G. Lerner
Research: DNA
Left handed DNA
Most DNA that you have seen is likely a right-handed helix (B-DNA or A-DNA). We have known for decades that DNA can also form left-handed structures, including
Z(WC)-DNA (proposed by Earlham Alum Allen Ansevin '51!). Modern research has shown that left-handed DNA is surprisingly common in biological contexts, and we are currently studying the mechanisms by which DNA transitions from a right-handed to a left-handed structure.
Note: this page is currently being updated. For recent papers, see my
Google Scholar Profile.